Background: Skin cancers is prevailing and constantly increasing by the day in Nigeria, to add to the worry is the length/duration it takes to detect it and attendant delay in terms of diagnosis. This work is meant to assess the levels of awareness and the influencing factors related to skin cancer knowledge in Nigeria in a broader note. Methods: This prevailing investigation and rudiments was carried out in Benue State North Central Nigeria through the medium of a validated questionnaire, which contained several items – demographics, skin cancer knowledge, source of the knowledge of cancer, valid information, cancer sources, preventive and treatment measures on skin cancer Results: Out of the 560 respondents engaged in the study, 2.1% had never heard of skin cancer, 18.5% had a low performance of skin cancer knowledge, 79.3% had a good score on the knowledge of skin cancer. In the same way, 75.1% of the respondents have good and general knowledge of cancer ranging from heard about it, reliable and credible source of information and can identify those who suffer from it. About 22.5% of the participants do know nothing about it. In the same vein, 45.5% of the participants score high on the true source and cause of cancer, 54% knows nothing about the cause. The participants score 59.5% on the facts about skin cancer leaving 16.2% with little knowledge of the proven causes and 24.3% are completely ignorance on the causes. On the knowledge and the use of the preventive measures, only 21% of the participant know and some time use the preventive measure, 49.4% of the participants do not know the measures and invariably cannot practice same while 29.6% are totally ignorant on the subject of prevention techniques. 57.7% of the participants had a high score on skin cancer treatment knowledge, 18.3% had little or no knowledge of the treatment and 24% know nothing about the treatment methods. Conclusions: Consider the lack of knowledge and the underestimations of skin cancer and its attendance risks in our study area, efforts are highly recommended to strengthened skin cancer surveillance behaviors in Nigeria to prevent its destructive arms on the populace especially the young people.
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